Research Paper Volume 11, Issue 18 pp 7442—7456

Analyses of an epigenetic switch involved in the activation of pioneer factor FOXA1 leading to the prognostic value of estrogen receptor and FOXA1 co-expression in breast cancer

Figure 3. FOXA1 analysis in breast cancer (Oncomine database). The online Oncomine analysis tool (red: overexpression, blue: down-expression) was used to compare FOXA1 expression levels in breast cancer specimens with matched normal specimens. The thresholds for significant probes for each microarray dataset included a two-fold difference in expression between cancer and normal samples and P < 0.0001. The box plot compares FOXA1 expression in cancer samples (right) and matches normal (left) samples generated from the Oncomine database.