Research Paper Volume 11, Issue 18 pp 7442—7456

Analyses of an epigenetic switch involved in the activation of pioneer factor FOXA1 leading to the prognostic value of estrogen receptor and FOXA1 co-expression in breast cancer

Figure 7. (A) Co-expression of the FOXA1 gene as determined by cBioPortal. (B) Regression analysis between FOXA1 and ESR1 in breast cancer performed by cBioPortal. (C) Relationship between FOXA1 and ESR1 in breast cancer determined through bc-GenExMiner v4.0. (D) Heat map of FOXA1 and ESR1 mRNA expression across PAM50 breast cancer subtypes in TCGA database, identified by UCSC Xena. (E) Correlation between FOXA1 and ESR1 mRNA expression in the TCGA database, identified by UCSC Xena.