Figure 8. FOXA1 expression is negatively regulated by DNA methylation. (A) Heatmap including BRCA PAM50 subtypes, ER status, and BRCA DNA methylation data from TCGA-BRCA were identified by the UCSC Xena browser. (B) DNA methylation patterns in different subtypes of breast cancer (cluster 1 to 5, the lowest to the highest). (C) The expression of FOXA1 in different BRCA DNA methylation clusters.