Figure 5. Thickness of cortex evaluated by T2-weighted images detected by 7 Tesla MRI system. The cortical thickness was measured by Image J software on T2-weighted images obtained from Paravision software. (A) Representative T2-weighted images used for measurement of cortical thickness (red line segment indicates the measured regions). (B) Results showed that cortical thickness was reduced in TLR2KO mice and AD-TLR2KO mice compared with WT mice (&: TLR2KO vs. WT, p<0.05; +: AD-TLR2KO vs. WT, p<0.05). (n= 4~6 / group).