Genomic deletion of TLR2 induces aggravated white matter damage and deteriorated neurobehavioral functions in mouse models of Alzheimer’s disease

Chao Zhou; Xiaoyu Sun; Yuting Hu; Jiaxing Song; Shuyu Dong; Delian Kong; Yuqiao Wang; Xiaodong Hua; Jingjing Han; Yan Zhou; Guoliang Jin; Xinxin Yang; Hongjuan Shi; Zuohui Zhang; Fang Hua

doi:doi:10.18632/aging.102260

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Research Paper Volume 11, Issue 17 pp 7257—7273

Genomic deletion of TLR2 induces aggravated white matter damage and deteriorated neurobehavioral functions in mouse models of Alzheimer’s disease

Figure 7. Levels of synaptophysin (Syn) and PSD95 in mouse brains. (A) Representative image of Western blots for Syn. (B) Representative image of Western blots for PSD95. (C, D) There was no significant difference in the levels of Syn (C) and PSD95 (D) between AD and AD-TLR2KO mice. (n= 6 / group).