Research Paper Volume 11, Issue 20 pp 8777—8791

LncRNA MALAT1 shuttled by bone marrow-derived mesenchymal stem cells-secreted exosomes alleviates osteoporosis through mediating microRNA-34c/SATB2 axis

Figure 7. Schematic representation of the regulatory role of BMSCs-derived exosomal MALAT1 in osteoporosis by mediating miR-34c/SATB2 axis. BMSCs-derived exosomal MALAT1 acts as a sponge of miR-34c to increase the expression of SATB2, which is conducive to promoting osteogenesis in osteoporosis.