Research Paper Volume 11, Issue 18 pp 7553—7569

Long non-coding RNA TUG1 enhances chemosensitivity in non-small cell lung cancer by impairing microRNA-221-dependent PTEN inhibition

Figure 4. Overexpression of TUG1 enhances chemosensitivity of NSCLC cells to DDP in nude mice. (A) tumor volume changes in mice with NSCLC; (B) tumor weight in mice with NSCLC; (C) TUNEL staining of apoptosis in NSCLC mice (× 400); (D) the expression of autophagy-related proteins in NSCLC tissues in vivo. * p < 0.05 versus the NC group; ** p < 0.01.