Research Paper Volume 11, Issue 18 pp 7707—7722

Single-cell RNA-seq reveals RAD51AP1 as a potent mediator of EGFRvIII in human glioblastomas

Figure 6. RAD51AP1 is an oncogene in glioma. (A) RAD51AP1 highly coincides with EGFRvIII in scRNA-seq data. (B) GSEA was performed to estimate RAD51AP1 expression in gliomas of different clinical grades. (C) Uni- and multivariable Cox analyses were performed to evaluate the role of RAD51AP1 in gliomas in the CGGA database, while GO and KEGG analyses were employed to profile the pathways of RAD51AP1-related genes in the CGGA database.