Research Paper Volume 11, Issue 18 pp 7805—7816

A novel chalcone derivative exerts anti-inflammatory and anti-oxidant effects after acute lung injury

Figure 2. Effects of compound 33 on mice with lipopolysaccharide (LPS)-induced acute lung injury (ALI). (A) Mean body weights for the two groups over 15 days. (B) Survival rates of mice with LPS-induced ALI. (C) Lung tissues were stained with hematoxylin and eosin to show morphological changes. (D) Degree of tissue edema was evaluated using lung wet-to-dry weight ratios. (E) Total protein amounts in cell-free supernatant of bronchoalveolar lavage fluid (BALF). Data are presented as means ± standard error of the mean (SEM; n = 3–6). # P <0.05, ## P <0.01, compared to the control group. * P <0.05, ** P <0.01, compared to the LPS group.