Research Paper Volume 11, Issue 18 pp 7805—7816

A novel chalcone derivative exerts anti-inflammatory and anti-oxidant effects after acute lung injury

Figure 3. Effects of compound 33 on LPS-induced inflammation and oxidative damage in mice. (AC) Levels of proinflammatory cytokines in cell-free supernatant of the BALF as determined using enzyme-linked immunosorbent assays. (D) Superoxide dismutase (SOD) activity in the BALF. Protein levels of the proinflammatory mediators (E) iNOS and (F) COX2 in the lungs. Data are presented as means ± SEM (n = 3–6). # P <0.05, ## P <0.01, compared to the control group. * P <0.05, ** P <0.01, compared to the LPS group.