Research Paper Volume 11, Issue 20 pp 8825—8844

ACADS acts as a potential methylation biomarker associated with the proliferation and metastasis of hepatocellular carcinomas

Figure 3. ACADS is associated with the proliferation, migration, and invasion of HCC cells. (A) The corresponding figure shows that siRNAs downregulate the mRNA and protein expression of ACADS in Huh7 and HCCLM3 cell lines. (B) The knockdown of ACADS significantly enhances both the migration and invasion potentials in Huh7 and HCCLM3 cells. Representative images are shown at the bottom. (C and D) CCK-8 assays and colony assays showed that the proliferation of HCC cells was enhanced following the knockdown of ACADS. (* P<0.05, **P<0.01).