Research Paper Volume 11, Issue 20 pp 8845—8859

COL6A6 interacted with P4HA3 to suppress the growth and metastasis of pituitary adenoma via blocking PI3K-Akt pathway

Figure 4. The effect of COL6A6 on the growth and metastasis of xenograft tumor. (A and B) The tumor size was obtained from nude mice; (C and D) Tumor volume and tumor weight of nude mice were analyzed; (E and F) The expression of COL6A6 in xenograft tumor tissues were detected by western blotting; (G and H) The expression of Ki-67 in xenograft tumor tissues were detected by immunohistochemistry staining; (I and J) The expression of E-cadherin, vimentin, and N-cadherin were measured by western blotting. **P<0.01, ***P<0.001, compared with NC group.