Research Paper Volume 11, Issue 18 pp 7978—7995

GSK-3β and ERK1/2 incongruously act in tau hyperphosphorylation in SPS-induced PTSD rats

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Figure 6. SPS does not influence neuronal and/or synaptic density. (A) Hippocampal sections were stained by Nissl staining to assess neuronal density (upper row scale bar=500μm, middle and lower row scale bar=100μm). (BD) Quantitative analysis was performed, and SPS didn’t induce the neuronal death in CA1(B), CA3(C) and DG(D). (EH) WB analysis showed no significant changes in the level of synaptophysin, synapsin1 and PSD95. Data are presented as mean ± SEM, n=3.