Research Paper Volume 11, Issue 20 pp 8892—8910

TGF-β receptor inhibitor LY2109761 enhances the radiosensitivity of gastric cancer by inactivating the TGF-β/SMAD4 signaling pathway

Figure 3. Effects of LY on radiosensitivity of GC cell lines. (A) CCK-8 assay: the proliferation of RR and parental GC cells influenced by LY. (B) CCK-8 assay: the proliferation of GC cells influenced by LY with or without irradiation treatment. (C) Flow cytometry analysis: the cell apoptosis in GC cells influenced by LY with or without irradiation treatment. (D) Clonogenic survival analysis: the clonogenic ability of GC cells influenced by LY with or without irradiation treatment. All data represent three independent experiments, mean ± SEM, **P<0.01, ***P<0.001, ****P<0.0001.