Research Paper Volume 11, Issue 21 pp 9264—9279

Dopaminergic neuron injury in Parkinson’s disease is mitigated by interfering lncRNA SNHG14 expression to regulate the miR-133b/ α-synuclein pathway

Figure 6. MiR-133b negatively regulated α-syn expression. (A) The complementary base pairs between miR-133b and α-syn 3′-UTR. (B) Regulatory role of miR-133b on α-syn expression was verified by using dual luciferase reporter gene assay. (C) The levels of α-syn mRNA and protein were analyzed with qRT-PCR and western blotting, respectively. **P<0.01 compared with pre-NC or NC.