Research Paper Volume 11, Issue 21 pp 9264—9279

Dopaminergic neuron injury in Parkinson’s disease is mitigated by interfering lncRNA SNHG14 expression to regulate the miR-133b/ α-synuclein pathway

Figure 8. SNHG14/miR-133b affected DA neuron activity that damaged by rotenone. MN9D cells were transfected with various vectors and treated with or without rotenone. (A) Cells viability was detected by CCK8 assay. (B) Percentage of apoptotic cells was quantified using flow cytometry. (C) Relative LDH activity. (D) The level of ATP in each group was measured. (E) The level of ROS in each group was measured. **P<0.01 compared with control; ##P <0.01 compared with Ro+si-control; &&P<0.01 compared with Ro+si-SNHG14+NC.