Research Paper Volume 11, Issue 20 pp 8969—8981

Expression and significance of miR - 20b in retinal photoreceptor cells exposed to PCB1254

Figure 5. FGF2 and GRB2 are the target genes of miR-20b. (AB) 24 hours after transfection, the mRNA and protein levels of FGF2 and GRB2 in the miR-20b overexpression group were significantly reduced. (CD) The opposite effects were observed in the silencing group. (EF) After 24 hours of exposure, FGF2, GRB2 expression levels were decreased with increasing concentrations (statistically significant in the 1 mg/L group). (*: P<0.05).