Research Paper Volume 11, Issue 20 pp 9013—9024

Melatonin induces progesterone production in human granulosa-lutein cells through upregulation of StAR expression

Figure 5. Melatonin levels in follicular fluid are positively correlated with P4 levels in serum. Follicular fluid (FF) melatonin levels and serum P4 levels were examined using ELISA (n = 50), and Pearson’s correlation analysis was performed to assess their relationship. FF melatonin levels were positively correlated with serum P4 levels both on (A) hCG administration day, and (B) oocyte pick-up (OPU) day.