Research Paper Volume 11, Issue 20 pp 9013—9024

Melatonin induces progesterone production in human granulosa-lutein cells through upregulation of StAR expression

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Figure 5. Melatonin levels in follicular fluid are positively correlated with P4 levels in serum. Follicular fluid (FF) melatonin levels and serum P4 levels were examined using ELISA (n = 50), and Pearson’s correlation analysis was performed to assess their relationship. FF melatonin levels were positively correlated with serum P4 levels both on (A) hCG administration day, and (B) oocyte pick-up (OPU) day.