Research Paper Volume 11, Issue 21 pp 9310—9327

Baicalein attenuates OVA-induced allergic airway inflammation through the inhibition of the NF-κB signaling pathway

Figure 1. Baicalein relieves OVA-induced AHR in mice. (A) The construction of a model of OVA-induced allergic airway inflammation. Mice were sensitized by OVA/Al(OH)3 on day 0 and day 14, while from days 25 to 31, the mice were exposed to 1% OVA aerosol for 7 consecutive days. (B) Airway responsiveness was assessed as the mean response of mechanically ventilated mice to increased doses of Mch (mean ± SEM; n = 6 per group; **P < 0.01 compared with the control group).