Figure 3. Silencing of ARHGAP27P1 promoted proliferation, cell cycle progression, invasion and migration, and inhibited apoptosis of HGC-27 cells. Scramble siRNA (si-NC) or ARHGAP27P1 siRNA (si-ARHGAP27P1) was transfected into HGC-27 cells. (A) Knockdown efficiency of si-ARHGAP27P1 was determined by RT-qPCR. (B) Cell proliferation was determined by cell counting assays in ARHGAP27P1-silencing HGC-27 cells. (C) Colony formation assays. (D) Cell apoptosis assays. (E) Cell cycle assays. (F) Wound healing assays. (G) Transwell migration and invasion assays. *P < 0.05, **P < 0.01 versus si-NC.