Research Paper Volume 11, Issue 21 pp 9424—9441

Neuroprotective effects of protocatechuic aldehyde through PLK2/p-GSK3β/Nrf2 signaling pathway in both in vivo and in vitro models of Parkinson's disease

Figure 6. PCA improved mitochondrial function and inhibited ROS production in MPP+-incubated SH-SY5Y cells. (A) Mitochondrial membrane potential (MMP) was measured using the JC-1 probe through the 590 nm/530 nm fluorescence emission ratio. (B) Activity of mitochondrial complex I in each group. (C) Mitochondria-generated ROS levels in each group. Data were presented as mean ± S.D., n = 6; **P< 0.01, *P < 0.05 vs. control group; #P< 0.05 vs. MPP+group.