Research Paper Volume 11, Issue 21 pp 9556—9568

Dexmedetomidine inhibits neuronal apoptosis by inducing Sigma-1 receptor signaling in cerebral ischemia-reperfusion injury

Figure 1. Dexmedetomidine improved neurological function after CIRI. Neurological deficit scores. Data are shown as the mean ± standard error of the mean (SEM), n = 12 per group. *P < 0.05 compared with the sham group; #P < 0.05 compared with the MCAO group. Sham operation group, Sham group; dexmedetomidine administration group, Dex group; MCAO model control group, MCAO group; MCAO + dexmedetomidine administration group, MCAO + Dex group.