Figure 5. Potentially functional roles of candidate lncRNAs participating in ccRCC tumorigenesis. (A–B) Relative expression of lncRNAs was verified in cell lines by RT-qPCR. (C–F) Four modules of protein-protein interaction networks. (G–J) Intersections of these modules with respect to biological process, molecular function, and KEGG and Reactome pathways. (K) Potential mechanistic schematic diagram of the role of candidate lncRNAs in kidney cancer tumorigenesis. Each experiment was performed at least three times and data are presented as the mean ± SEM. P<0.05 was considered to indicate a statistically significant difference. *P<0.05, **P<0.01, ***P<0.001 and ****P<0.0001. lncRNAs, long non-coding RNA.