Figure 4. USP22 silencing suppresses in vitro GC cell migration and invasion. (A–B) Transwell assay results show total number of (A) migratory and (B) invasive BGC-823 and HGC-27 cells that are untransfected (Mock) or transfected with 100 nM siNC or siUSP22-1 at 48 h after transfection. Note: Magnification: 200×; Data are expressed as mean ± SD of three replicates. *p < 0.05 compared with mock or siNC group.