Figure 5. Data were presented as the mean ± SD. * p<0.05, *** p<0.01. (A) The results of cell proliferation in 5 glioblastoma cell lines and HL-7702 treated with different doses of ENMD-2076 (0, 0.5, 1, 2, 4, 8μM) for 24, 48, 72 hours. (B–C) Colony formation assay results of ENMD-2076 anti-proliferative effects in C6, LN18 and T98G cells for 2 weeks. (D–E) ENMD-2076 suppressing the migration of LN18, T98G cells in the scratch assay. The wound-healing images represented the migration capacity of glioblastoma cells.