Research Paper Volume 11, Issue 21 pp 9767—9777

Resistin enhances angiogenesis in osteosarcoma via the MAPK signaling pathway

Figure 1. Clinical significance of resistin expression in tissue specimens from patients with osteosarcoma. (A) Tumor specimens were subjected to immunohistochemistry (IHC) evaluations with anti-resistin monoclonal antibody and the staining intensity was graded as 0 (no positive cell staining), 1 (1–24%, weakly positive), 2 (25–49%, moderately positive), or 3 (50–100%, strongly positive). (B) Positive correlations were observed between levels of resistin and VEGF-A expression.