Research Paper Volume 11, Issue 21 pp 9767—9777

Resistin enhances angiogenesis in osteosarcoma via the MAPK signaling pathway

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Figure 1. Clinical significance of resistin expression in tissue specimens from patients with osteosarcoma. (A) Tumor specimens were subjected to immunohistochemistry (IHC) evaluations with anti-resistin monoclonal antibody and the staining intensity was graded as 0 (no positive cell staining), 1 (1–24%, weakly positive), 2 (25–49%, moderately positive), or 3 (50–100%, strongly positive). (B) Positive correlations were observed between levels of resistin and VEGF-A expression.