Figure 1. Genomic amplification of USP5 in ovarian cancer was correlated with overall survival of patients. (A) CNV analysis of USP family genes in TCGA cohort (n=579). (B) Kaplan-Meier survival analysis between patients with and without USP15 amplification using TCGA cohort (n=564). (C) USP15 mRNA levels were higher in samples with USP5 amplification than in those without USP5 amplification. (D) USP5 copy number alteration in patients of cohort 1 by real-time PCR analysis (n=80). The cut-off for amplification was set at 4 copies per tumor cell. (E) Kaplan-Meier survival analysis between patients with and without USP15 amplification using cohort 1 (n=80).