Research Paper Volume 11, Issue 21 pp 9862—9874

Genome-wide association study identifies SIAH3 locus influencing the rate of ventricular enlargement in non-demented elders

Figure 4. Rs11620312 associated with other phenotypes longitudinally. The minor allele (C) of rs11620312 was associated with the increased rates of EF decline (B, PBonf = 0.037) and FDG hypometabolism (C, PBonf = 0.029), however it was not associated with the change rates of MEM (A, PBonf = 0.18) and hippocampus volume (D, PBonf = 1.16) over time. Abbreviation: MEM = cognitive score for memory; EF = cognitive score for executive functioning; FDG = 18F-fluorodeoxyglucose.