Research Paper Volume 11, Issue 21 pp 9875—9892

Promising therapeutic effect of thapsigargin nanoparticles on chronic kidney disease through the activation of Nrf2 and FoxO1

Figure 1. The mRNA levels of ER stress- and autophagy-related molecules were analyzed in the renal tissue of healthy individuals and CKD patients. The mRNA levels of ERN1, XBP1, EIF2AK3, ATF6 (A), BECN1 and ATG5 (B) were evaluated. Statistical differences were analyzed using a two-sample t-test.