Research Paper Volume 11, Issue 24 pp 11803—11813

LncRNA HIF1A-AS2 promotes osteosarcoma progression by acting as a sponge of miR-129-5p

Figure 5. miR-129-5p suppressed osteosarcoma cell proliferation, cell cycle progression and invasion. (A) The expression of miR-129-5p in osteosarcoma cell lines (U2OS, SoSP-M, SaOS-2, MG-63) and an osteoblast cell line (hFOB) was measured by qRT-PCR. (B) Overexpression of miR-129-5p suppressed MG-63 cell growth. (C) Ectopic expression of miR-129-5p decreased the S phase of MG-63 cells compared to that of the scramble group. (D) Ectopic expression of miR-129-5p decreased MG-63 cell invasion. (E) The relative invasive cells are shown. *p<0.05, **p<0.01 and ***p<0.001.