Research Paper Volume 11, Issue 24 pp 11814—11828

Circadian clock associates with tumor microenvironment in thoracic cancers

Figure 2. Circadian clock widely impacts the cancer-related signalling pathways. (A) Links between core circadian clock genes and hallmark signalling pathways. (B) The combined percentage of pathway activity. Abbreviations: LUAD, lung adenocarcinoma; LUSC, lung squamous cell carcinoma; ESCA, esophageal carcinoma); A, activate; I, inhibit.