Research Paper Volume 11, Issue 24 pp 12165—12176

GPX1, a biomarker for the diagnosis and prognosis of kidney cancer, promotes the progression of kidney cancer

Figure 6. The knockdown of GPX1 levels inhibits the proliferation capability of renal cancer cells in vitro. (A) As shown by immunoblotting results, the expression levels of GPX1 were knocked down by transfecting sh-GPX1 plasmids. (B) CCK8 results showed that GPX1 knockdown significantly inhibited the proliferation of renal cancer cells. (C) GPX1 knockdown obviously reduced the colony formation ability of renal cancer cells. (***, P < 0.001, **, P < 0.01, *, P < 0.05, compared with the respective control).