Research Paper Volume 11, Issue 24 pp 12345—12360

Circular RNA SMO sponges miR-338-3p to promote the growth of glioma by enhancing the expression of SMO

Figure 5. MiR-338-3p inhibited the growth of glioma cells. (A) miR-338-3p expression with different treating, miR-338-3p mimics and miR-338-3p inhibitor. (B) MiR-338-3p inhibitor promoted SMO mRNA while mimic inhibited it. (CF) MiR-338-3p mimics inhibited cells proliferation, migration and invasion, while enhanced cells apoptosis according to assays of the CCK8, flow cytometry and Transwell. *P<0.05, compared with NC.