Research Paper Volume 11, Issue 24 pp 12345—12360

Circular RNA SMO sponges miR-338-3p to promote the growth of glioma by enhancing the expression of SMO

Figure 6. SMO has same effect on cells activity as circSMO742. (A, B) SMO knockdown inhibited SMO mRNA expression while the presence of circSMO742 or miR-338-3p inhibitor could reverse the expression caused by SMO knockdown. (CF) SMO suppression suppressed proliferation, migration, invasion but promoted apoptosis of U-87 MG cells. *P<0.05, v.s. NC.