Research Paper Volume 11, Issue 24 pp 12345—12360

Circular RNA SMO sponges miR-338-3p to promote the growth of glioma by enhancing the expression of SMO

Figure 7. The inhibitory role of circSMO742 knockdown was verified in vivo. (AC) The tumors in circSMO742 suppression group were significantly smaller than that of NC group after 20 days injections growth. (D) The Ki67 was stained to detect the proliferation of cells. (EG) CircSMO742 and SMO protein expression in circSMO742 knockdown (sh-Circs) groups were reduced while miR-338-3p was elevated. (H) Survival percentages of nude mice with different treatments. **P<0.01, compared with control.