Research Paper Volume 11, Issue 24 pp 12412—12427

CircRNA_100367 regulated the radiation sensitivity of esophageal squamous cell carcinomas through miR-217/Wnt3 pathway


Figure 7. Effect of circRNA_100367 on tumor growth of KYSE-150R cells under radiation. KYSE-150R cells were stably transfected with Sh-circRNA_100367 or negative control (Circ) and then were subcutaneously inoculated into nude mice. 10 days after inoculation, mice were irradiated with 6 Gy X-ray. (A, B) Representative pictures and volumes of excised tumors. (C) The protein levels of E-cadherin, vimentin, snail, Wnt3 and β-catenin in excised tumors were measured by western blot. (D) A schematic diagram representing the role and mechanism of circRNA_100367 in radiation sensitivity of ESCC.