Research Paper Volume 11, Issue 24 pp 12497—12531

Age-related changes in eye lens biomechanics, morphology, refractive index and transparency

Figure 2. Lens volume and aspect ratio for mouse lenses between 2–30 months of age. Lines on the plots reflect mean ± SD of n = at least 8 lenses per age. The graph next to the data plots shows the 95% confidence interval. Any comparisons not crossing the dotted line are statistically significant (p < 0.05). (A) Lens volume (mm3) from mice between 2–30 months of age. The volume increases steadily between 2-8 months of age and more slowly after 8 months. (B) The lens aspect ratio (axial/equatorial diameter) drops slightly between 2 to 4 months of age and then remains unchanged with age. Mouse lenses become slightly more spherical between 2 and 4 months.