Research Paper Volume 11, Issue 24 pp 12497—12531

Age-related changes in eye lens biomechanics, morphology, refractive index and transparency

Figure 3. Nuclear volume and fraction for mouse lenses between 2–30 months of age. Lines on the plots reflect mean ± SD of n = at least 8 lenses per age. The graph next to the data plots shows the 95% confidence interval. Any comparisons not crossing the dotted line are statistically significant (p < 0.05). (A) The volume (mm3) of the lens nucleus steadily increases with age. (B) Since nuclear volume increases more than lens volume with age, the nuclear fraction (nuclear/lens volume) increases with age.