Research Paper Volume 11, Issue 24 pp 12600—12623

Genome-wide global identification of NRF2 binding sites in A549 non-small cell lung cancer cells by ChIP-Seq reveals NRF2 regulation of genes involved in focal adhesion pathways

Figure 2. NRF2 TFBS motif enrichment analysis. (A) Enrichment of known motifs (target motifs vs. background known motifs) showing the top-ranked motif logos. (B) Logo showing the top ranked de novo motif identified using HOMER. (C) STAMP analysis results showing the logo of the de novo motif identified by HOMER (lower) highly matched the NFE2L2-JASPAR binding motif (upper).