Research Paper Volume 12, Issue 2 pp 1272—1284

FOXO4-DRI alleviates age-related testosterone secretion insufficiency by targeting senescent Leydig cells in aged mice

Figure 1. Expression of FOXO4 in human testes detected by immunofluorescent staining. (A) FOXO4 was expressed in the interstitial or peritubular cells of human testes, but not within the seminiferous tubules. (B) FOXO4+ cells expressing the Leydig cell markers StAR and CYP11A1. Scale bar: 100 μm.