Figure 2. Correlation analysis between serum GH/IGF-1 levels and brain tissue volume in patients with GH-PA and patients with NonFun-PA groups. The normalized GM volume (nGMV) shows significant positive correlation with GH (A) and IGF-1 (B) in patients with GH-PA. The normalized WM volume (nGWV) shows no significant correlation with GH (C) or IGF-1 (D) in patients with GH-PA. The normalized CSF volume (nCSFV) shows significant negative correlation with GH (E) and IGF-1 (F) in patients with GH-PA. In patients with NonFun-PA, nGMV, nWMV, and nCSFV show no significant correlation with GH/IGF-1 (G–L).