Research Paper Volume 12, Issue 2 pp 1563—1576

SENP1 is a crucial promotor for hepatocellular carcinoma through deSUMOylation of UBE2T

Figure 5. SENP1 deSUMOylates UBE2T. (A) Comparative analysis of UBE2T in different species. (B) The effect of SENP1 knockout on SUMO-UBE2T complex was determined using co-Immunoprecipitation. (C) The effect of UBE2T-overexpression and UBE2T-K8R mutation co-expressed with SENP1 knockout on SUMO-UBE2T complex was determined using co-Immunoprecipitation.