Research Paper Volume 12, Issue 2 pp 1624—1642

TPGS-1000 exhibits potent anticancer activity for hepatocellular carcinoma in vitro and in vivo

Figure 1. Effect of TPGS1000 on viability and proliferation of hepatocarcinoma cells. (A) Morphology of four HCC cell lines (HepG2, Hep3B Huh7 and Bel7402) treated with different concentrations of TPGS (0, 11, 22 and 44 μM), scale bar = 100 μm. (B) The structure of TPGS1000. (C) HCC cells were cultured in the presence of various concentrations (0–66 μM) of TPGS for 48 h. Cell viabilities were measured using CCK8. The line graph represents the percent viable cells compared to the vehicle-treated cells. (DG) Growth curves of four HCC cell lines were plotted from cell counts under different concentrations of TPGS.