Research Paper Volume 12, Issue 2 pp 1808—1827

ISG20 serves as a potential biomarker and drives tumor progression in clear cell renal cell carcinoma

Figure 3. Identification of hub genes via LASSO cox regression analysis. (A) Partial likelihood deviance of OS for the LASSO coefficient profiles. (B) LASSO coefficient profiles of the nine key genes for OS. (C) Partial likelihood deviance of DFS for the LASSO coefficient profiles. (D) LASSO coefficient profiles of the nine key genes for DFS. (E) ISG20, HJURP, and FOXM1 were identified as hub genes according to the LASSO cox regression analysis of OS and DFS. LASSO: least absolute shrinkage and selection operator; OS: overall survival; DFS: disease-free survival.