Figure 5. ISG20 expression level was associated with various clinicopathological parameters in ccRCC. The expression of ISG20 was positively correlated to TNM stage (A) Grade (B) T stage (C) N stage (D) and M stage (E). High expression of ISG20 predicted poor OS (F) and DFS (G) in ccRCC. (H, I) The expression of ISG20 could effectively differentiate ccRCC from normal renal tissues. ccRCC: clear cell renal cell carcinoma; TNM: Tumor Node Metastasis; OS: overall survival; DFS: disease-free survival. Data are represented as mean ± SD. ****, P < 0.0001; ***, P < 0.001; **, P < 0.01; *, P < 0.05.