Research Paper Volume 12, Issue 2 pp 1808—1827

ISG20 serves as a potential biomarker and drives tumor progression in clear cell renal cell carcinoma

Figure 5. ISG20 expression level was associated with various clinicopathological parameters in ccRCC. The expression of ISG20 was positively correlated to TNM stage (A) Grade (B) T stage (C) N stage (D) and M stage (E). High expression of ISG20 predicted poor OS (F) and DFS (G) in ccRCC. (H, I) The expression of ISG20 could effectively differentiate ccRCC from normal renal tissues. ccRCC: clear cell renal cell carcinoma; TNM: Tumor Node Metastasis; OS: overall survival; DFS: disease-free survival. Data are represented as mean ± SD. ****, P < 0.0001; ***, P < 0.001; **, P < 0.01; *, P < 0.05.