Figure 4. Kaplan-Meier survival analyses on differential P4HB expression groups with OS in the included 532 KIRC patients (A). The patients were stratified into high and low P4HB groups by quarter (25% upper vs 75% lower). Compared with low mRNA expression of P4HB, high P4HB expressions were significantly correlated with poor OS (p < 0.0001); The interaction network of P4HB protein with other proteins (B). CALR, HSP90B1, HSPA5, PPIB, MTTP, P4HA3, PDIA6, PRKCSH, and CALU physically/functionally connect P4HB. Note: The interaction network was obtained from STRING database.