Figure 4. Transcriptional expression of AURKA and CDC20 in HCC tumor tissues and adjacent normal liver tissues. (A) Transcriptional level of AURKA expression was found to be significantly higher in 369 HCC tissues compared with 160 normal tissues (p<0.0001). (B) Transcriptional expression of AURKA was significantly correlated with AJCC stages, patients in more advanced stages expressed higher levels of AURKA mRNA. (C) Transcriptional expression of AURKA was significantly correlated with ISUP grade, patients in more advanced grade score expressed higher levels of AURKA mRNA. Highest AURKA mRNA expression was found in stage 3 or grade 4. (D) Transcriptional level of CDC20 expression was found to be significantly higher in 369 HCC tissues compared with 160 normal tissues p<0.0001). (E) Transcriptional expression of CDC20 was significantly correlated with AJCC stages, patients in more advanced stages tended to express higher levels of CDC20 mRNA. (F) Transcriptional expression of CDC20 was significantly correlated with ISUP grade, patients in more advanced grade score expressed higher levels of CDC20 mRNA. Highest CDC20 mRNA expression was found in stage 3 or grade 4.