Figure 6. (A–H) significantly correlated genes and hallmarks pathways in HCC obtained by GSEA. A total of 100 significant genes were obtained by GSEA with positive and negative correlation. The most involved significant pathways included base excision repair, cell cycle, DNA replication, mismatch repair, oocyte meiosis, pyrimidine metabolism, RNA degradation, and spliceosome. (I) Transcriptional expression profiles of the 100 significant genes are shown in the heat map.