Research Paper Volume 12, Issue 7 pp 5625—5639

LncRNA 2310043L19Rik inhibits differentiation and promotes proliferation of myoblast by sponging miR-125a-5p

Figure 9. A schematic model of lncRNA 2310043L19Rik-mediated proliferation of myoblast through sponging miR-125a-5p. In brief, E2F3 can promote proliferation of C2C12 myoblasts. In addition, miR-125a-5p inhibits E2F3 expression and attenuates the function of E2F3 by directly targeting the 3’-UTR of E2F3. lncRNA 2310043L19Rik inhibits differentiation through a certain pathway. lncRNA 2310043L19Rik promotes proliferation of myoblast cells by attenuating function of miR-125a-5p.