Inhibition of miR-19a partially reversed the resistance of colorectal cancer to oxaliplatin via PTEN/PI3K/AKT pathway

Ye Zhang; Xinxin Liu; Junying Zhang; Yuanyuan Xu; Jie Shao; Yue Hu; Peng Shu; Haibo Cheng

doi:doi:10.18632/aging.102929

← Back

Research Paper Volume 12, Issue 7 pp 5640—5650

Inhibition of miR-19a partially reversed the resistance of colorectal cancer to oxaliplatin via PTEN/PI3K/AKT pathway

Figure 1. Oxaliplatin resistance of SW480/R and HT29/R. (A) MTT assays were performed to evaluate the cytotoxicity of different concentrations of oxaliplatin (0~30 μM) to SW480, SW480/R, HT29 and HT29/R. *P<0.05. (B) IC50 of oxaliplatin to SW480, SW480/R, HT29 and HT29/R. *P<0.05.